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Pathak, K.
- In Vitro Permeation Studies on Clonazepam from Proniosomes Based Niosomes for Transdermal Delivery
Abstract Views :188 |
PDF Views:96
Authors
Affiliations
1 Rajiv Academy for Pharmacy, Mathura, IN
1 Rajiv Academy for Pharmacy, Mathura, IN
Source
Journal of Pharmaceutical Research, Vol 8, No 1 (2009), Pagination: 61-65Abstract
Proniosmal gel of clonazepam (CNZ) for transdermal delivery to provide controlled drug release was prepared by phase coacervation method using non ionic surfactants, cholesterol and egg lecithin. The formulations were investigated for surface morphology by scanning electron microscopy (SEM), particle size, entrapment efficiency, in-vitro drug release and in-vitro drug permeation. SEM enabled visualization of proniosomes of clonazepam and the vesicle size was found to be in the range of 1492.32 - 9865.68 nm with entrapment efficiency as high as 72.9%. Amongst the ten formulations designed, F2 and F6 were selected as the optimized formulations and incorporation of egg lecithin increased the entrapment efficiency of the selected formulations to more than 90%. The fabricated matrix transdermal patch exhibited more than 70% drug release in 24 hours.Keywords
Clonazepam, Proniosomes, Transdermal Delivery, In Vitro Permeation.Full Text
- A Study to Assess the Knowledge Regarding Psychological Problems of Premenstrual Syndrome and its Management among Adolescent girls at Selected PU College of Belgaum City, with a View to Develop Informational Booklet
Abstract Views :228 |
PDF Views:0
Authors
Affiliations
1 KLEU Institute of Nursing Sciences, Nehru Nagar, Belgaum – 590 010, Karnataka, IN
1 KLEU Institute of Nursing Sciences, Nehru Nagar, Belgaum – 590 010, Karnataka, IN
Source
Asian Journal of Nursing Education and Research, Vol 7, No 1 (2017), Pagination: 9-11Abstract
Many women experience various premenstrual physical, emotional, or behavioral changes, which at times reach such levels of severity that they may have substantial social impact upon the woman herself, her associates, and her work. So a descriptive study was undertaken to assess the knowledge regarding psychological problems of premenstrual syndrome and its management among adolescent girls in selected preuniversity colleges of Belgaum city. The findings revealed that, maximum number of subjects 54(67.5%) were in the age group 16-17 years, maximum number of subjects 40(50) belongs to Hindu religion, majority of the subjects were in class 11th (92.5%), maximum subjects (95%) belongs to joint family, maximum subjects have attained menarche 32(40%), maximum subjects members suffering from premenstrual syndrome 48(60%),majority of subjects have length of menstrual flow 54(67.5%), majority of the subjects having knowledge about premenstrual syndrome 46(34%). The informational booklet significantly brought out their improvement in the knowledge regarding psychological problems of premenstrual syndrome and its management.Keywords
Premenstrual Syndrome, Knowledge, Adolescent, Premenstrual Dysphoric Disorder, Informational Booklet, Psychological Impact.
- Effect of Vermicompost on Growth of Crysophogan Zizanioides on Manganese Mine Dump of Central India
Abstract Views :82 |
PDF Views:0
Authors
Affiliations
1 Research Scholar, School of Environmental science and Engineering, IN
2 Professor, Department of Mining Engineering, Indian Institute of Technology, Kharagpur, IN
3 General Manager, MOIL Limited, Nagpur, IN
1 Research Scholar, School of Environmental science and Engineering, IN
2 Professor, Department of Mining Engineering, Indian Institute of Technology, Kharagpur, IN
3 General Manager, MOIL Limited, Nagpur, IN
Source
Journal of Mines, Metals and Fuels, Vol 69, No 11 (2021), Pagination: 400 - 410Abstract
The utilization of crysophogan zizanioides in the management of mine-site dumps opens a new doorway for carbon sequestration and mitigation of soil erosion. Crysophogan zizanioides, a.k.a vetiver grass, is a densely tufted grass from Poaceae family of giant grasses. These grasses are known for its tolerance to extremely high levels of heavy metals and can grow in tropical and temperate regions around the world. Hence, the present study attempts to utilize the barren manganese dumps around the Dongri Buzurg mine area in central India as a carbon sink patch by vegetating vetiver grass. It was found that the nutrient content of the hangwall and footwall of the existing dump was lacking in N (29.33kg/acre) and P (58.73 kg/acre) for sustaining the potential growth of plant species, also the organic carbon content was found to be around 0.10% which should ideally be around 1.12%. As the dump requires longer roots compared to its shoots, for providing stability and control of soil erosion, the study focuses on this aspect of vetiver growth. It was observed that as the percentage vermicompost increases than shoot/root (S/R) ratio decreases. The study on the control sample indicated a ratio of 3.33 over a period of 60 days indicating poor root growth without any vermicompost supplement on the other hand a 50% vermicompost sample indicated a ratio of 1.24 over the same period of time. This study developed an empirical formula using statistical analysis tools to determine the optimum S/R ratio at different per cent vermicompost.
Keywords
Manganese waste dump, vetiver grass, vermicompost, low-cost soil improvement techniques.References
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- Tahir Lawan Dalorima, Abd Jamil Zakaria, Ali Majrashi, Khairil Mahmud, Khamsah Suryati Mohd, Hasbullah Muhammad, Mohammad Moneruzzaman Khandaker, (2018): Impacts of vermicomposting rates on growth, yield and qualities of red seedless watermelon, Australian Journal of crop Science AJCS 12(11): 1765-1773.
- Xiao Deng, Xiang Meng , Yi Li, Chun-Yuan Wu1, Qin- Fen Li. (2017): Effect of Vermicompost on the Physicochemical Properties of Coastal Saline Soil. International Forum on Energy, Environment Science and Materials (IFEESM 2017). Advances in Engineering Research, Vol.120.